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Does anyone have any hard evidence that B12 vials really deteriorate after the use by date, or is it just a marketing game

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However, some people are at greater risk: People who eat a restrictive diet that does not contain enough B12

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NICE guidelines recommend hydroxocobalamin 1 mg intramuscularly three times weekly for 2 weeks (without neurological involvement) or on alternate days until no further improvement (with neurological symptoms)

Its defined chemical structure makes it suitable for analytical testing, reference standards, and research applications in laboratory settings